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by dissolving a tablet in 10 Cc. of water, adding 10 drops of urine and boiling moderately during 3 to 5 minutes, when in the presence of diabetic sugar, an indigo blue color results. The reaction is not vitiated by the presence of uric acid, creatinin, glyconic acid, gall-pigments, nor medicinal substances, such as rhubarb, senna, turpentine, iodine, salicylic acid, etc.Pharm. Ztg., Jan. 3, 1900, 8.

Nucleol is stated to be pure nucleïn, and is supplied in form of a whitish powder, readily soluble in warm water, but insoluble in alcohol-its solubility in water being augmented by the addition of dilute alkali. If freshly precipitated mercuric oxide is added to an aqueous solution of nucleïn, prepared from yeast, it is gradually dissolved, solution being accelerated by heating. On addition of absolute alcohol to the solution so obtained, a solid compound of nucleïn and mercury is obtained in the form of a voluminous precipitate. In a similar manner, compounds of nucleïn with copper, silver and iron may be obtained, all of these being characterized by ready solubility in water, particularly with the aid of heat. These compounds have been introduced under the following names : Cuprol, a green powder, containing 6 per cent. Cu.

Ferrinol, a cinnamon brown powder, containing 6 per cent. Fe.
Nargol, a light brownish-white powder, containing about 10 per cent. Ag.
Mercurol, a brownish-white powder, containing 10 per cent. Hg.

These compounds do not precipitate albuminoids, and are, therefore, of special value for the treatment of wounds, being free from the more or less irritant action of other compounds of the same metals.-Phar. Ztg., May 5, 1900, 346.

Nural, the new name for the nutrient and digestive specialty heretofore marketed under the name of Nutrol.-Pharm. Ztg., Jan. 3, 1900, 8.

Osteogen is the name given by Ziegenbruch to a syrup of iron and calcium phosphate, containing in 100 Cc., 3.1022 Gm. calcium phosphate and 0.2661 Gm. acid ferric phosphate, and recommended in the treatment of rhachitis and similar ailments.—Phar. Ztg., Feb. 10, 1900, 116.

Oxymethylphthalimid.-Obtained by heating phthalimid with formaldehyde, with or without pressure. Composition CH,.CO.CO.NCH2OH.

Used as an antiseptic for wounds.

Ozalin water. This is a carbonated water containing magnesium dioxide.-Pharm. Ztg., Jan. 13, 1900, 37.

Papillin, recommended by Dr. R. Th. Melenreis as a hair restorative, is obtained by digesting 15 Gm. of orris root with 100 Gm. alcohol, and adding 50 Gm. spirit of lavender and 15 Gm. tincture of benzoin.-Pharm. Ztg., May 12, 1900, 366.

Perl-Collodium, according to B. Crede, a somewhat slowly drying collodion, containing no ether and forming a stronger and more adhesive pellicle than ordinary collodion.-Pharm. Ztg., June 28, 1900, 483.

Phenacetinsulphonate of Sodium.-Preparation analogous to that of "acetanilidsulphonate of sodium" (which see). A micro-crystalline, white powder, possessing the advantage over phenacetin in its solubility in water and innocuousness. Used as an antipyretic.

Phenegol.-The mercuro-potassium salt of nitroparasulphonic acid. A red-brown, odorless and tasteless powder, containing 33 per cent, of mercury, and soluble in cold water in all proportions. Used as an antiseptic.

p-Phenetidin citrate, primary (monophenetidin citrate). Obtained by mixing equivalents of p-phenetidin and citric acid, either in substance or in solution (alcohol). It forms white, odorless prisms, having the taste of citric acid, which are readily soluble in water, but sparingly in alcohol. Used in rheumatic and febrile ailments.

Phenoleum-An antiseptic fluid, composed mainly of purified American (oil of? Rep.) turpentine, perfumed with a volatile oil, presumably oil of melissa.

Pictolin is a mixture of liquefied gases, probably mainly composed of sulphurous acid, introduced by Pictet for the fumigation of vessels, storehouses, etc.-Pharm. Ztg., Feb. 28, 1900, 166.

Plasmon (Kascon).—Composition and Nutrient Value.-According to the experiments of Dr. M. Wintgen, the milk preparation known under the name of "plasmon " is composed of: water, 10.66 per cent.; nitrogenous substances (nitrogen, 11.07 × 6.37), 70.51 per cent.; fat, 4.40 per cent. ; milk sugar, 4.20 per cent.; inorganic substances (ash), 6.96 per cent. The ash is composed of 5.14 per cent. potassa, 16.78 per cent. soda, 1.61 per cent. magnesia, 32.68 per cent. lime, 38.56 per cent. phosphoric acid, 3.60 per cent. carbonic acid, 1.70 per cent. chlorine, and 1.62 per cent. sulphuric acid. The alkali salts naturally existing in milk being for the greater part removed with the whey during the process of preparing plasmon, its alkali content is largely due to added sodium bicarbonate. The author regards plasmon as being a valuable albuminoid dietetic for the sick, the digestible nitrogenous substances contained in it being utilized to the extent of 95 per cent.-Apoth. Ztg., Dec. 9, 1899, 740; from Ztschr. f. Unters. d. Nahr. u. Genussm., 1899, 761.

Propolisin, a red-brown, somewhat opalescent fluid, is recommended as a disinfectant and antiseptic, and claimed by its introducer to be a product of the dry distillation of beeswax. - - Pharm. Ztg., May 5, 1900, 347.

Protargol-Use of Glycerin to Expedite Solution in Water-According to Kopp concentrated solutions of protargol are obtained with great ease and rapidity if the protargol is preliminarily triturated with an equal weight of glycerin before adding the water. The proportions of such a solution may be as follows: Protargol, 2, glycerin, 2, tepid distilled water, 3 parts. Apoth. Ztg., Dec. 23, 1899, 775; from Münch. Med. Wochenschr., 1899, No. 50.

Pyrantin-Soluble, according to Gioffredi the sodium salt of pyrantin (p-ethoxyphenylsuccinimid) employed as an antiseptic in the same way as pyrantin. Pharm. Ztg,, July 1, 1899, 460.

Quinine Chloride-sulphate, produced on account of its easy solubility in water (equal weight) for hypodermic use. It is obtained by dissolving 30 Gm. of the ordinary quinine sulphate in 24 Cc. of hydrochloric acid, sp. gr. 1,050, and evaporating the solution to crystallization. It is an odorless, bitter, crystalline powder, containing the same percentage (74 per cent.) of quinine as the official sulphate. - Pharm. Ztg., June 28, 1900, 483.

Resaldol A New Intestinal Antiseptic.-A. Eichengrün has given the name "resaldol" to a condensation product of u-chlormethyl-salicylaldehyde and resorcin. It is a light brown powder, soluble in alcohol, acetone, acetic ether, and hot glacial acetic acid, but insoluble in water, ether, ligroin, benzol and chloroform. It has powerful bactericidal properties in alkaline media as well as in neutral solutions, and is therefore particularly useful as an intestinal antiseptic.-Apcth. Ztg., April 14, 1900, 254.

Resorbin Mercury is a substitute for mercurial ointment prepared with the new specialty "resorbin" as a base in the proportion of 1 : 3.—Pharm. Ztg., March 3, 1900, 173.

Sapodermin is a medicinal soap, said to contain mercury in form of albuminate (caseinate) and claimed to possess strong bactericidal properties, while devoid of irritant, caustic or poisonous properties, and therefore constituting an innocuous substitute for corrosive sublimate soap for antiseptic washings and for the treatment of parasitic affections of the skin. Pharm. Ztg., Feb. 10, 1900, 116.

Saponaceous Mercurial Ointment.-Composed, according to Schuster, of mercury, 33.33; white olein soap, 12.66; filtered suet, 18.co; filtered lard, 36.00. The proportions of the last two are varied according to season.

Septicidin is a serum preparation used in the treatment of erysipelas in hogs, hog cholera and chicken cholera, obtained from the blood of highly immunized animals. If preserved cool, but free from frost, it retains its activity for at least half a year.--Pharm. Ztg., Jan. 10, 1900, 27.

Sicco-Trade-Name for Dry Hæmatogen.--Schneider describes dry hæmatogen, to which he has given the name of "sicco," as forming redbrown, tasteless and odorless crystals, which keep well without any addition of glycerin, alcohol, or other preservatives. It is free from all blood impurities, digested by the gastric juice to the extent of 99 per cent., and contains 89.32 per cent. of albumen, 0.332 per cent. of organic iron, 2.6 per cent. of mineral matter, and 0.11 per cent. of fat. It dissolves readily in cold water, its solution being coagulable by heat.

To make liquid hamatogen, So parts of sicco are dissolved in 400 parts of distilled water; a solution of 2 parts of sodium hydroxide in 278 parts

of water is then added, and this is followed by 120 parts of syrup, 120 parts of 90 per cent. alcohol, and 5.5 parts of aromatic tincture. After standing three days, the solution is filtered.-Pharm. Ztg., 1900, 87.

Sidnal is the trade name for a new gout remedy composed of piperazine (-diethylenediamine) and kinic acid. It is given either by itself, or in combination with phenocoll, lithium compounds, etc., and in its combination with lithium citrate has heretofore been known under the name of urosin.-Pharm. Ztg., March 7, 1900, 182.

Sodium Superoxide Soap.-Prepared by incorporating from 2 to 20 per cent. of sodium superoxide with a mixture of 2 parts of liquid paraffin and 7 parts of perfectly dry medicinal soap. Used in acne and rosacea pustulosa.

"Solfuro Oil"-A Product from Olive Residues-According to a recent Consular (British) Report, extensive works exist in the Milazzo (Italy) district for the manufacture of a product from the residue of olives, from which the oil has been extracted. This product is called "solfuro oil" and is used in the manufacture of soap. The final residue is used as fuel. The average annual production of this by-product is about 1,000

tons.

Spleniferrin-A Preparation from the Spleen of Cattle.-Dr. B. Rhodes calls attention to a preparation obtained by mixing the pulped and dried spleen of neat cattle with a certain proportion of iron in form of albuminoids, the spleen itself containing in the case of older animals nearly 5 per cent. of iron, or nearly thrice as much as that of young animals. The new chalybeate is recommended by reason of its ready assimilation into the human organism, and because it may be given for a long period without inconvenience.-Apoth. Ztg., Dec. 13, 1899, 749; from Dtsch. Med. Ztg. (Ther. Beil.), 1899, 83.

Staphylase is the name given by Doyen to a product obtained by him in the form of a yellow powder from beer-yeast, of which he claims it to be the active principle, and which it is intended to replace for therapeutic use (see also "Levurine ").-Pharm. Ztg., March 17, 1899, 211. Sudol-A mixture of adeps lane and glycerin, containing 3 per cent. of aldehyde. Recommended for foot-sweat.

Sudoral, recommended as an addition to foot-baths for sweating feet, is an acid fluid, giving a strong sulphur reaction, and is said to contain benzoic, boric and tartaric acid in a medium composed of alum solution.— Pharm. Ztg., Jan. 3, 1900, 8.

Sulfosot.-A syrup containing 5 per cent. of guaiacolsulphonate of potassium and 5 per cent. of cresolsulphonate of potassium. Given in tubercu losis in teaspoonful doses.

Tartaric acid diphenylester.-Obtained by the condensation of tartaric acid and phenol by means of phosphoric oxychloride, and constitutes fine,

silky-glistening needles (m. p. 101°-102° C.), having a faint aromatic odor, which are insoluble in water, difficultly soluble in cold alcohol, but readily soluble in hot alcohol, in ether and in glycerin. Used in the treatment of gout.

Tenalgin is stated to be a mixture of the alkaloids of the areca nut, and is recommended by its introducer as a remedy for tape-worm in animals. -Pharm. Ztg., Feb. 10, 1900, 116.

Thymolcarbonate.-Obtained by passing phosgene gas into a 20 per cent. sodium hydrate solution holding a calculated quantity of thymol in solution. A nearly tasteless, light yellow, syrupy liquid, intended for the convenient administration of thymol.

Tortoine-A New Cotoine Derivative. A product resulting from the reaction of formaldehyde upon cotoine has been introduced into medicine under the name of " tortoine." It occurs in small, yellow, tasteless crystals, having a faint, cinnamon odor. It is insoluble in water, sparingly soluble in alcohol and ether, but readily dissolved by chloroform, acetone, glacial acetic acid and alkalies. It is given -purpose not named — in doses of 0.25 Gm. three times in 24 hours.-Pharm., Journ. May 19, 1900; 530; from Journ. de Pharm. d'Anvers, 56, 138.

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Vegetale. A yellow mass, semi-liquid at the ordinary temperature, but retaining its fluidity for quite a while after melting. It is said to be impure cotton-oil-stearin.

Zinol. A mixture of zinc acetate, 1 part and alumnol, 4 parts. Used as a wash (31000) in gonorrhoeal affections of women.

MATERIA MEDICA.

A. VEGETABLE DRUGS.

GENERAL SUBJECTS.

The British Pharmaceutical Society's Materia Medica Museum-Notes on Some of its Contents.—It having been suggested to Dr. E. M. Holmes, Curator of the British Pharmaceutical Society's Museum, that he communicate some information concerning the Museum and its contents as being useful to students of pharmacy, the more particularly since the Museum catalogue has been out of print for some years, Dr. Holmes has consented to write a series of papers on this subject, beginning with a general introduction, in which he discusses the scope, contents and arrangement of the Museum. This, as intended, is of interest mainly to students that have access to the Museum; but the subsequent papers which have appeared in

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