Bioinformatics and Functional Genomics
John Wiley & Sons, 2005. 3. 4. - 792페이지
Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science.
다른 사람들의 의견 - 서평 쓰기
서평을 찾을 수 없습니다.
PART II GENOMEWIDE ANALYSIS OF RNA AND PROTEIN
PART III GENOME ANALYSIS
Appendix GCG for Protein and DNA Analysis
Solutions to SelfTest Quizzes
기타 출판본 - 모두 보기
accession number acid sequence algorithm amino acid amino acid identity analysis annotation approach archaea arrow bacteria Bioinformatics biological BLAST search cDNA cell cerevisiae Chapter chromosome clones ClustalW cluster codon coli compared complete genome database search deﬁned described DNA sequence domain encoding Entrez eukaryotic example exons FIGURE ﬁnd ﬁrst function GenBank gene expression genetic genome sequence genomic DNA homologous human disease human genome identiﬁed identify includes introns lipocalins matrix microarray microarray data molecular molecules motifs mouse mRNA multiple sequence alignment mutation NCBI nucleotide ofthe OMIM organisms ORNL orthologs output pairwise alignment Pfam phenotype phylogenetic tree predicted proﬁle prokaryotes protein families protein sequences protein structure protein-coding genes proteome PSI-BLAST quence RBP4 regions residues samples score selected sequence data server signiﬁcant species speciﬁc syndrome Table tein tion transcripts UniGene viral virus viruses yeast
356 페이지 - As many more individuals of each species are born than can possibly survive; and as, consequently, there is a frequently recurring struggle for existence, it follows that any being, if it vary however slightly in any manner profitable to itself, under the complex and sometimes varying conditions of life, will have a better chancs of surviving, and thus be naturally selected.
185 페이지 - Brazma, A., Hingamp, P., Quackenbush, J., Sherlock, G., Spellman, P., Stoeckert, C., Aach, J., Ansorge, W., Ball, CA, Causton, HC...
396 페이지 - ... branches of various sizes may represent those whole orders, families, and genera which have now no living representatives, and which are known to us only in a fossil state.
396 페이지 - As buds give rise by growth to fresh buds, and these, if vigorous, branch out and overtop on all sides many a feebler branch, so by generation I believe it has been with the great Tree of Life, which fills with its dead and broken branches the crust of the earth, and covers the surface with its ever-branching and beautiful ramifications.
722 페이지 - Gene The fundamental physical and functional unit of heredity. A gene is an ordered sequence of nucleotides located in a particular position on a particular chromosome that encodes a specific functional product (ie, a protein or RNA molecule).
396 페이지 - The green and budding twigs may represent existing species ; and those produced during each former year may represent the long succession of extinct species. At each period of growth, all the growing twigs have tried to branch out on all sides, and to overtop and Kill the surrounding twigs and branches, in the same manner as species and groups of species have tried to overmaster other species in the great battle for life.
219 페이지 - Lewis DB, Tibshirani R, Sherlock G, Chan WC, Greiner TC, Weisenburger DD, Armitage JO, Warnke R, Staudt LM, et al. (2000). Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling.
464 페이지 - Invertebrata) their incredible numbers, their universal distribution, their insatiable voracity, and that it is the particles of decaying vegetable and animal bodies which they are appointed to devour and assimilate. Surely we must in some degree be indebted to these ever-active invisible scavengers, for the salubrity of our atmosphere. Nor is this all : they perform a still more important office in preventing the gradual diminution of the present amount of organized matter upon the earth.
396 페이지 - The limbs divided into great branches, and these into lesser and lesser branches, were themselves once, when the tree was small, budding twigs ; and this connexion of the former and present buds by ramifying branches may well represent the classification of all extinct and living species in groups subordinate to groups.
396 페이지 - The affinities of all the beings of the same class have sometimes been represented by a great tree. I believe this simile largely speaks the truth.