Bioinformatics and Functional GenomicsJohn Wiley & Sons, 2005. 3. 4. - 792ÆäÀÌÁö "Introduction to Bioinformatics" ist eine breit angelegte Einführung in die Bioinformatik. Der Band gliedert sich in drei Abschnitte zu biologischen Sequenzdaten, kompletten Genomen und bioinformatischen Ansätzen zur Problemlösung bei der Sequenzanalyse, Microarrays und Krankheiten des Menschen. Erfahrung im Umgang mit rechnergestützten Methoden wird nicht vorausgesetzt. "Introduction to Bioinformatics" kombiniert Theorie und praktische Anwendung in einem ausgewogenen Verhältnis. Jedes Kapitel enthält Problemstellungen, Computeraufgaben, Software Pakete, Web Links und einen praktischen "How To"-Abschnitt, der genau erklärt, wie man frei zugängliche Software nutzen kann. Der Band erläutert darüber hinaus auch die Schwachstellen der verschiedenen Ansätze. Mit drei ausführlichen Beispielen. Mit einem Glossar. Mit einem Lösungsteil zu den Problemstellungen. Mit einer Bibliographie weiterführender Literatur. |
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... Find-a-Gene, 9 Key Bioinformatics Websites, 10 Suggested Reading, 12 References, 12 Access to Sequence Data and Literature Information, 15 Introduction to Biological Databases, 15 GenBank: Database of Most Known Nucleotide and Protein ...
... Find-a-Gene, 9 Key Bioinformatics Websites, 10 Suggested Reading, 12 References, 12 Access to Sequence Data and Literature Information, 15 Introduction to Biological Databases, 15 GenBank: Database of Most Known Nucleotide and Protein ...
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... FIND-A-GENE 9 Organization of The Chapters Suggestions For Students and Teachers: Web Exercises and Find-a-Gene.
... FIND-A-GENE 9 Organization of The Chapters Suggestions For Students and Teachers: Web Exercises and Find-a-Gene.
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... find new lipocalins. Teaching bioinformatics is notable for the diversity of students learning this new discipline. Each chapter provides background on the subject matter. For more advanced students, several key research papers are ...
... find new lipocalins. Teaching bioinformatics is notable for the diversity of students learning this new discipline. Each chapter provides background on the subject matter. For more advanced students, several key research papers are ...
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... find out the sequence of human retinolbinding protein (RBP4). A fundamental distinction is that both DNA and protein sequences are stored in discrete databases. Furthermore, within each database, sequence data are represented in a ...
... find out the sequence of human retinolbinding protein (RBP4). A fundamental distinction is that both DNA and protein sequences are stored in discrete databases. Furthermore, within each database, sequence data are represented in a ...
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... find the entry for RBP, go to bhttp:liwww.ncbi.nlm.nilhggy, The goal of the UniGene (unique gene) project is to create one unique entry for each select UniGene on the sidebar} gene and to collect all the ESTs associated with that gene ...
... find the entry for RBP, go to bhttp:liwww.ncbi.nlm.nilhggy, The goal of the UniGene (unique gene) project is to create one unique entry for each select UniGene on the sidebar} gene and to collect all the ESTs associated with that gene ...
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PART II GENOMEWIDE ANALYSIS OF RNA AND PROTEIN | 155 |
PART III GENOME ANALYSIS | 395 |
Epilogue | 695 |
Appendix GCG for Protein and DNA Analysis | 697 |
Glossary | 717 |
Solutions to SelfTest Quizzes | 735 |
Subject Index | 737 |
Author Index | 753 |
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accession number acid sequence algorithm amino acid amino acid identity analysis annotation approach archaea arrow bacteria Bioinformatics biological BLAST search cDNA cell cerevisiae Chapter chromosome clones ClustalW cluster codon coli compared complete genome database search defined described DNA sequence domain encoding Entrez eukaryotic example exons FIGURE find first function GenBank gene expression genetic genome sequence genomic DNA homologous human disease human genome identified identify includes introns lipocalins matrix microarray microarray data molecular molecules motifs mouse mRNA multiple sequence alignment mutation NCBI nucleotide ofthe OMIM organisms ORNL orthologs output pairwise alignment Pfam phenotype phylogenetic tree predicted profile prokaryotes protein families protein sequences protein structure protein-coding genes proteome PSI-BLAST quence RBP4 regions residues samples score selected sequence data server significant species specific syndrome Table tein tion transcripts UniGene viral virus viruses yeast
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356 ÆäÀÌÁö - As many more individuals of each species are born than can possibly survive; and as, consequently, there is a frequently recurring struggle for existence, it follows that any being, if it vary however slightly in any manner profitable to itself, under the complex and sometimes varying conditions of life, will have a better chancs of surviving, and thus be naturally selected.
185 ÆäÀÌÁö - Brazma, A., Hingamp, P., Quackenbush, J., Sherlock, G., Spellman, P., Stoeckert, C., Aach, J., Ansorge, W., Ball, CA, Causton, HC...
396 ÆäÀÌÁö - ... branches of various sizes may represent those whole orders, families, and genera which have now no living representatives, and which are known to us only in a fossil state.
396 ÆäÀÌÁö - As buds give rise by growth to fresh buds, and these, if vigorous, branch out and overtop on all sides many a feebler branch, so by generation I believe it has been with the great Tree of Life, which fills with its dead and broken branches the crust of the earth, and covers the surface with its ever-branching and beautiful ramifications.
722 ÆäÀÌÁö - Gene The fundamental physical and functional unit of heredity. A gene is an ordered sequence of nucleotides located in a particular position on a particular chromosome that encodes a specific functional product (ie, a protein or RNA molecule).
396 ÆäÀÌÁö - The green and budding twigs may represent existing species ; and those produced during each former year may represent the long succession of extinct species. At each period of growth, all the growing twigs have tried to branch out on all sides, and to overtop and Kill the surrounding twigs and branches, in the same manner as species and groups of species have tried to overmaster other species in the great battle for life.
219 ÆäÀÌÁö - Lewis DB, Tibshirani R, Sherlock G, Chan WC, Greiner TC, Weisenburger DD, Armitage JO, Warnke R, Staudt LM, et al. (2000). Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling.
464 ÆäÀÌÁö - Invertebrata) their incredible numbers, their universal distribution, their insatiable voracity, and that it is the particles of decaying vegetable and animal bodies which they are appointed to devour and assimilate. Surely we must in some degree be indebted to these ever-active invisible scavengers, for the salubrity of our atmosphere. Nor is this all : they perform a still more important office in preventing the gradual diminution of the present amount of organized matter upon the earth.
396 ÆäÀÌÁö - The limbs divided into great branches, and these into lesser and lesser branches, were themselves once, when the tree was small, budding twigs ; and this connexion of the former and present buds by ramifying branches may well represent the classification of all extinct and living species in groups subordinate to groups.
396 ÆäÀÌÁö - The affinities of all the beings of the same class have sometimes been represented by a great tree. I believe this simile largely speaks the truth.