The legs go to sleep while goes to sleep with sudden The right foot goes to sleep. sitting, especially early in the anything is held or carried. The hands frequently go to sleep at Cramp and paralysis which are attendant upon so many maladies, are often the natural consequences of determination of blood to the brain and spinal marrow. The pressure upon these central organs produces an alteration in their vital force, and thus occasions one or other of the above named conditions. I have already enlarged upon these anomalies, and must now confine myself to the few following observations. Among the spasmodic symptoms of Sepia, the twitching and jerking movements, the cramp of the calves, soles and toes are especially well marked; the two last named symptoms indicate an affection of the entire nervous system. The feeling as if gone to sleep, and numbness, are very prominent among the paralytic conditions; actual paralysis seldom ensues, and when it does, it rapidly disappears. Heaviness of the eyelids and legs, painful weariness and stiffness, are the precursors of the condition in question. 9. DROPSY. Dropsical effusion is in most cases the final result of a vitiated condition of the blood, which may have existed for a long time. Whenever there is an impeded flow of the venous blood, whenever the liver and heart are diseased, and the circulation is obstructed, serious injury will ere long be produced. The few following symptoms seem to indicate very clearly both local and general dropsy. Swelling of the whole body, of the face, abdomen, legs and arms, to the wrist, without thirst, with great dyspnoea, for three weeks with fever, alternating every two and three days with chilliness and heat at irregular hours, even during the night, heat and perspiration all over. Swelling of the wrist joint, in the evening, in the bend of the elbow, and about the ankle; the joints were numbed when moving; the swelling disappeared early in the morning, but the parts were painful when touched. The swelling of the leg increased to the knee while sitting and standing, it disappeared on walking. Swelling of the feet. The feet swell with much walking. We will now pass in review the principal kinds of pains and sensations which Sepia is capable of inducing in a healthy person. Tearing (head, ears, face, teeth, anus, urinary organs, genitals, chest, extremities). Drawing (head, ears, face, teeth, stomach, abdomen, genitals, chest, back, extremities). Tension (head, face, mouth, abdomen, anus, chest, back, extremities). Shooting, stitches (head, eyes, ears, nose, face, teeth, throat, stom ach, abdomen, anus, urinary organs, genitals, chest, back, extremities.) Cutting (mouth, throat, stomach, abdomen, anus, urinary organs, genitals, lower extremities). Burning (eyes, teeth, mouth, throat, stomach, abdomen, anus, urinary organs, genitals, chest, extremities). Soreness (head, ears, nose, teeth, mouth, throat, abdomen, anus, genitals, chest, back, extremities). Pressure (head, eyes, ears, nose, face, teeth, throat, stomach, abdomen, bronchi, chest, back, extremities). Dull pains (head, teeth and stomach). Twitches (head, eyes, abdomen, genitals, back, extremities). Jerks (head, teeth, throat). Biting (eyes, teeth, mouth, throat, anus, urinary organs, lower extremities). Itching (head, eyes, ears, nose, face, abdomen, anus, urinary organs, genitals, chest, back, extremities). Tickling (bronchi, face, extremities). Pulsation and beating (head, teeth, stomach, chest). Squeezing (head, abdomen). Spasmodic pain (anus, lower extremities). Spasmodic pains (face, stomach). Pressing, and pressing together (head, genitals, back). Pressing, outwards (ears, stomach, anus). Boring (head, stomach, lower extremities). Digging (head, teeth, abdomen). Rending (eyes, urinary organs). Pinching (throat, urinary organs). Rumbling (stomach, abdomen). Painful weariness (back). Bruised pain (of the extremities). Pain as of dislocation (back, upper extremities). On reviewing the whole of the subject and endeavouring to ascertain the properties of Sepia, we shall arrive at the following conclusions: 1st. Sepia has its sphere of action in the portal system, in which it causes obstructions. 2nd. Most of its symptoms indicate a high degree of venous congestion. 3rd. It is characterised by torpidity and depression, often ending in perfect exhaustion of the vital powers. 4th. Hence it is suitable in mild and easy dispositions, therefore especially for women. 5th. The affections arise and increase in severity, mostly in the evening and at night, during and immediately after a meal. 6th. The affections either disappear during, or are alleviated by, active exercise, and by pressure of the painful part. 7th. The affections are often accompanied with chilliness. 8th. Great sensitiveness of the skin to cold air. We will now proceed to review, in a few words, some distinguishing marks between Sepia and its closely related remedies. DIFFERENT DIAGNOSTIC INDICATIONS. Pulsatilla and Nux vomica stand next to Sepia. Whilst these remedies, which Hahnemann placed amongst the Poly chrests, evince their healing powers, both in acute and chronic diseases, and hence must possess a greater and more extensive sphere of action, we have already seen that the curative action of Sepia is principally observed in chronic maladies, or in such acute diseases which arise from a chronic morbid process. The similarity of action is attributable to the great influence which these remedies have on the sympathetic nerve. But the action of Pulsatilla and Nux occurs under very different conditions, and the abdominal disorders for the most part arise from other morbid affections. These two remedies influence almost the entire range of organic life, and their most prominent symptoms are not by any means centred in the venous system. Hence its symptoms must be referred to an entirely different type of disease from those of Sepia. On the whole, it may be observed here, that the character of torpor and depression is not peculiar to Puls. or Nux, but on the contrary, it is often found that they cause a great excitement of the vascular and nervous systems, inducing fever and a state of congestion far exceeding in violence what is produced by Sepia. The congestion not unfrequently terminates in inflammation, and the irritation of the nervous system attains a high degree of development-conditions which are not indicated by Sepia. Hence Nux is especially suitable for the sanguine temperament, and for men. Pulsatilla accords with Sepia in being suitable for mild, yielding dispositions, particularly for women, but its action on the sexual organs is in many points opposed to that of Sepia. Finally it may be still further observed, that the physiological action of Nux is more developed in the morning, Pulsatilla mostly in the evening, while the symptoms of Sepia are most frequently induced, or at least aggravated at night. Respecting the dose in which Sepia was administered, it may be added that the high dilutions were commonly employed. I have, according to circumstances, prescribed the decimal 6th, 12th, as well as the 30th, potencies 102 REVIEWS. Report of the Committee for Scientific Inquiries in relation to the Cholera Epidemic of 1854, presented to both Houses of Parliament by Command of Her Majesty. "My experience of this department, brief as it has been, strongly impressed me with a sense of the great want that is now felt of some systematic record of cases of Choleraic disease, their treatment and results, with a view to determine in so far as may be possible the best mode of meeting this formidable epidemic. Hitherto no successful attempt has been made to collect such a record; and as I find that my feeling of the want is very generally shared by the medical profession, I have obtained the sanction of Her Majesty' Government to the nomination of a Medical Council representing all branches of the profession **** By means of a return in the accompanying forms, the observations of all qualified practitioners on the cases that come under their care, may be collected and made available for determining the laws which regulate choleraic disease, and the effects of the different systems of treatment now in use." Thus wrote the President of the Board of Health to the medical profession, addressing to them this general invitation, and nominating a medical council having the highest national sanction, and intrusted with the greatest national responsibility. Let us see how the gentlemen selected for so high a trust discharged the duties it involved." Soon after your having constituted a medical council to advise the Board of Health on matters relative to the then prevailing epidemic of cholera, this council thought it convenient for the despatch of business that subjects referred to them should be distributed among certain committees of their number; and on this plan we, the undersigned, were requested to become a committee for the scientific purposes of this council. "Two special duties accordingly devolved upon us :-first, to suggest the institution of particular scientific inquiries which |